Canine salivary gland tumors are broadly classified into benign and malignant subtypes, with the vast majority of epithelial origin and malignant in appearance. Sebaceous adenoma of the parotid gland in a 2yearold male. Sebaceous lymphadenomas are rare and account for less than 1% of primary salivary gland tumors. The first ever case report this keeps sebaceous glands healthy and secretion of sebum under control. Sebaceous adenoma of salivary gland is an uncommon tumor that accounts for about 0. Fewer than 120 cases of sebaceous cell carcinoma have been reported at extraocular sites. Regardless of the location, sebaceous malignancies must. These rare tumors are mostly found in men older than 50 years. The major salivary glands consist of the parotid, submandibular, and sublingual glands. Media in category neoplasms of salivary glands this category contains only the following file. Although sebaceous glands in the salivary gland are not uncommon, the incidence of pri mary sebaceous tumor in the salivary gland is low. Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain com. Sebaceous lymphadenoma is a rare benign salivary gland tumour of uncertain histogenesis.
Morphologic evidence to support the lymph nodesalivary gland inclusion derivation of this. Sebaceous carcinoma is uncommon, with fewer than 400 cases reported. Very few cases have been reported in the literature and, here, we present one such rare case of epidermal cyst in the right parotid gland in a 62yearold female patient. Other less common sites include the submandibular gland, the minor salivary glands, stensons duct of. The malignant sebaceous gland carcinoma most commonly arises in the periocular area. Epidermal cysts are common skin lesions but they occur very rarely in the oral cavity, especially in the salivary glands. The salivary glands are classified as major or minor. Of submandibular neoplasms, pleomorphic adenoma ranks first, as in the parotid gland. Thompson salivary glands for dummies 1 salivary gland neoplasms lester d. Usually, lesions arise in the meibomian glands of the eyelid. Slsg may differentiate in descending order of frequency into sebaceous adenomas sa, sl, sc or slac. Regardless of the location, sebaceous malignancies must be considered aggressive neoplasms. By definition, all tumors have a lymphoid background and about onehalf have welldeveloped lymphoid follicles.
Sebaceous adenomas of salivary gland origin may be cystic or solid. Sebaceous carcinoma of the eyelid may be mistaken for inflammatory lesions, such as chalazion or blepharoconjunctivitis, resulting in a delayed. The risk factors include radiation exposure, familial predisposition. The majority of salivary gland neoplasms are benign, with malignant salivary tumors accounting for. Although salivary glands commonly contain sebaceous elements, it is rare for these to undergo neoplasia 5. A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. Salivary gland tumours or neoplasms are tumours that form in the tissues of salivary glands. Pdf sebaceous adenoma of the parotid gland researchgate. The sebaceous gland can sometimes be detected in normal major salivary glands, but sebaceous cellcontaining salivary gland neoplasms are rare. This is similar to other sebaceous salivary gland tumors. They are not often diagnosed prior to surgery, which could be due to their rarity and lack of.
We present a case of sebaceous carcinoma of the parotid gland which brings the total number of reported cases to 22. Tumors of minor salivary gland origin generally have a pushing growth pattern in contrast to squamous cell carcinoma and. Fine needle aspiration cytology of parotid swelling was suggestive of pleomorphic adenoma. Parotid gland, an exceptional localization of sebaceous carcinoma. Sebaceous adenoma of the submandibular gland is a very rare benign neoplasm 3. However, sebaceous gland tissue has been reported in salivary glands 3, which explains the discovery, although rare, of these tumors in such locations. Though the origin of sc within the major salivary glands is unclear, sc has mainly.
Sebaceous adenoma of the parotid gland in a 2yearold male kevin c. Papadimitriou, md, robert morales, md, and jeffrey s. It is observed in a wide age category of individuals the cause of formation of this salivary gland malignancy is generally unknown, but may be due to genetic factors. Mar 18, 2019 neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. The presence of sebaceous glands in salivary neoplasms is frequent, however, and in spite of this, salivary neoplasms constituted. Sebaceous lymphadenoma of the parotid gland mishra a. In addition to parotid gland, salivary gland sc has been identified in the submandibular gland, oral cavity, sublingual gland, vallecula, epiglottis, and hypopharynx, totaling 47 scs of salivary origin neoplasms. Salivary glands neoplasms click on any thumbnail to link to an enlarged image. Papillary cystadenoma and cystadenocarcinoma of salivary glands med oral patol oral cir bucal. Analysis of the clinical relevance of histological classification of.
Underlying wall was composed of sebaceous glands, adipose tissue, salivary gland tissue, and hyaline cartilage figures 3 and 4. Wed like to understand how you use our websites in order to improve them. However, it appears that some of the benign salivary gland tumours. Sebaceous adenomas are found in normal sebaceous glands that originate from the blind ends of intralobular ducts in otherwise normal salivary glands. Sebaceous neoplasms within salivary gland slsg are still rarer and likely arise as metaplasia as opposed to an origin from skin appendages. My journey into the world of salivary gland sebaceous neoplasms. So is synchronous occurrence of two benign or malignant neoplasms. Sebaceous glands definition of sebaceous glands by. They occur over a wide age range but the peak incidence is in 6th to 7th decades with a slight female predominance. Minor salivary tumors of the lip often mimic a mucocele or a mucous cyst but a softtofirm rubbery submucosal mass should raise suspicion for a minor salivary gland tumor. Papillary cystadenoma and cystadenocarcinoma of salivary glands e463 mass.
These sebaceous elements appeared to originate from the blindending intercalated and striated ducts. Unilocular cystic sebaceous lymphadenoma of the parotid gland. Sebaceous gland neoplasms is a descriptor in the national library of medicines controlled vocabulary thesaurus, mesh medical subject headings. Mucoepidermoid carcinoma low grade mucoepidermoid carcinoma high grade lymphomas. Sebaceous carcinoma of salivary gland origin is extremely rare and, because of its rarity, the clinicopathological. Considering the salivary glands, most cases involve the parotid gland and are rarely reported in the other major glands or intraorally 1, 2, 3, 4. Basaloidblue salivary gland tumors modern pathology. Image were created or taken from wikimedia commons i. This is a short video on the most common neoplasms tumors and cancers of the salivary glands.
Although sebaceous differentiation within the major salivary glands is a frequent histo. True sebaceous neoplasms sebaceous adenoma, sebaceoma, and sebaceous carcinoma are rare skin tumors, in contrast with sebaceous gland hyperplasia, which is encountered frequently in the general population, especially in sunexposed skin. In humans and other mammals, the skin operates a complex organ of numerous structures sometimes called the integumentary system serving vital protective and metabolic functions. Papillary cystadenoma and cystadenocarcinoma of salivary. Patients usually present with a welldefined painless swelling in front of or behind the ear parotid tumors. Sebaceous carcinoma of salivary gland origin is extremely rare and, because of its rarity, the clinicopathological characteristics and the histogenesis are not fully understood. Neoplasms of the sebaceous glands may be benign, such as sebaceous hyperplasia or sebaceous gland adenomas. A carcinoma ex pleomorphic adenoma was diagnosed in the left mandibular salivary gland of an 8yearold female spayed dog. In conclusion, the diagnosis of salivary gland lymphadenoma should be. Primary sebaceous tumors of salivary glands are extremely rare, although sebaceous glands are commonly present in parotid and submandibular glands.
If you continue browsing the site, you agree to the use of cookies on this website. A unique variant of the sebaceous lymphadenoma, socalled unilocular cystic sebaceous lymphadenoma or lymphoepithelial cyst with sebaceous differentiation, occurred in the parotid gland of a 38yearold man. Benign neoplasms of salivary glands i webpathology. These glands are composed of a number of different types of cells, and unregulated growth of these cells causes neoplasms.
There was a male prevalence in all types except malignancy of salivary glands. In our own series of 156 salivary gland tu mors, only 1 case was sebaceous adenoma. Synchronous sebaceous lymphadenoma with squamous cell. Sebaceous glands article about sebaceous glands by the. Dec 19, 2018 sebaceous carcinoma of salivary gland is a malignancy of the sebaceous cells, affecting mostly the major salivary glands. Some types of neoplasms have malignant characteristics, meaning that they can infiltrate into surrounding structures and can spread to distant regions, whereas others are benign. Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Basaloid or blue salivary gland tumors comprise a significant proportion of all tumors encountered in salivary gland, primary, metastatic as well as nonsalivarytype lesions. In humans, sebaceous glands occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. It can occur in any body site where sebaceous glands are present, but is most commonly found in the head and neck region, particularly in the periocular area. Some types of neoplasms have malignant characteristics, meaning that they can infiltrate into surrounding structures and can spread to distant regions, whereas others are. Jan 17, 2020 sebaceous glands are part of epidermal appendages. Tumors of the salivary glands constitute an important field of oral and maxillofacial pathology.
Sebaceous carcinoma is a rare malignant tumor of the sebaceous glands. Introduction lymphadenoma, which is classified as sebaceous and non sebaceous lymphadenoma based on the presence or absence of sebaceous differentiation, is a rare type of tumor of the salivary gland. Sebaceous carcinoma of salivary gland is a malignancy of the sebaceous cells, affecting mostly the major salivary glands. Sebaceous carcinoma of the parotid gland springerlink. Sebaceous differentiation in salivary gland tissue is not an uncommon finding. Comparative examination of androgen receptor reactivity. Sebaceous carcinoma seb is the most important malignant neoplasm of the eyelid because of the potential risk of metastasis.
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